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. 2023 Mar 24;13:4868. doi: 10.1038/s41598-023-32092-8

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Unsupervised cross-cancer hierarchical clustering. This cluster analysis was performed using the complete linkage method with Pearson correlation distance. BLCA Bladder urothelial carcinoma, BRCA Breast invasive carcinoma, COAD Colon adenocarcinoma, ESCA Esophageal carcinoma, GBM Glioblastoma multiforme, HNSC Head and neck squamous cell carcinoma, LGG Brain lower grade glioma, LIHC Liver hepatocellular carcinoma, LUAD Lung adenocarcinoma, LUSC Lung squamous cell carcinoma, OV Ovarian serous cystadenocarcinoma, PAAD Pancreatic adenocarcinoma, PRAD Prostate adenocarcinoma, READ Rectum adenocarcinoma, SARC Sarcoma, STAD Stomach adenocarcinoma, UCEC Uterine corpus endometrial carcinoma, GOF/wt Gene expression ratio (Log2) of TP53 gain-of-function mutant group to TP53 wild-type group, non-GOF/wt Gene expression ratio (Log2) of TP53 non-gain-of-function mutant group to TP53 wild-type group.