Table 5.
Number of studies reporting on aggregate primary outcomes and proportions of RCTs and studies with a significant primary outcome
| Aggregate primary outcome category (APOC) number of studies (% of total) | Specific primary outcomes | Number of RCTs (% of APOC) | Studies with a significant primary outcome* (% of APOC) |
|---|---|---|---|
| Functional capacity 37 (32.7) | • VO2 peak • 6MWT • Exercise capacity • Functional capacity • Heart rate |
28 (75.7) | 22 (59.5) |
| Patient adherence/compliance 35 (31.0) | • User adherence • User compliance • Patient engagement • User experience • Device utilization |
13 (37.1) | 7 (20.0) |
| Physical activity 27 (23.9) | • Number of steps • Daily step count • Exercise time • Sedentary time |
13 (48.1) | 14 (51.9) |
| Quality of life 14 (12.4) | • Quality of life • Blood pressure • Weight loss • Salt intake • Cardiac risk profile change • Anxiety/depression |
10 (71.4) | 4 (28.6) |
| Total: 113 | 64 (56.6) | 47 (41.6) |
6MWT, 6-minute walk test; APOC, aggregate primary outcome category; RCT, randomized clinical trial; VO2, oxygen uptake.
P < 0.05.