Table 2.
Electrocardiogram characteristics of heart transplant recipients by cardiac allograft rejection status in the retrospective cohort
| Median (Q1, Q3) or no. (%) of patients | |||||
|---|---|---|---|---|---|
| Characteristic | n | Overall (n = 7590) | ACR (positive) (n = 199) | ACR (negative) (n = 7391) | P-value |
| Heart rate | 7572 | 92 (84, 103) | 95 (87, 106) | 92 (83, 103) | 0.009 |
| PR interval (ms) | 7526 | 148 (132, 168) | 156 (134, 170) | 148 (132, 166) | 0.049 |
| QRS duration (ms) | 7572 | 100 (88, 128) | 108 (92, 133) | 100 (88, 128) | 0.002 |
| QT interval (ms) | 7572 | 372 (348, 398) | 376 (351, 404) | 372 (348, 398) | 0.15 |
| Corrected QT interval (ms) | 7572 | 460 (439, 483) | 473 (444, 496) | 460 (439, 483) | <0.001 |
| Sinus rhythm | 7572 | 5107 (67.4%) | 114 (57.3%) | 4993 (67.7%) | 0.003 |
| Sinus tachycardia | 7572 | 2007 (26.5%) | 66 (33.2%) | 1941 (26.3%) | 0.034 |
| Sinus bradycardia | 7572 | 38 (0.5%) | 3 (1.5%) | 35 (0.5%) | 0.077 |
| 1st degree AV block | 7572 | 303 (4.0%) | 13 (6.5%) | 290 (3.9%) | 0.094 |
| Mobitz Type 1 AV block | 7572 | 10 (0.1%) | 1 (0.5%) | 9 (0.1%) | 0.23 |
| Left bundle branch block | 7572 | 65 (0.9%) | 1 (0.5%) | 64 (0.9%) | 1.00 |
| Right bundle branch block | 7572 | 2939 (38.8%) | 91 (45.7%) | 2848 (38.6%) | 0.046 |
| Atrial fibrillation/flutter | 7572 | 218 (2.9%) | 12 (6.0%) | 206 (2.8%) | 0.015 |
| Pacemaker (ventricular pacing) | 7572 | 452 (6.0%) | 13 (6.5%) | 439 (6.0%) | 0.65 |
| Prolonged QT | 7572 | 515 (6.8%) | 18 (9.0%) | 497 (6.7%) | 0.20 |
| Non-specific interventricular conduction delay (IVCD) | 7572 | 229 (3.0%) | 9 (4.5%) | 220 (3.0%) | 0.20 |
P-values result from a Wilcoxon rank sum test (continuous variables) or Fisher’s exact test (categorical variables). The bold numeric values in the ‘P-value' column represent statistically significant results (i.e. P-value < 0.05). The bold values in the ‘characteristic' column represent group headings for example age, sex, time since, and race/ethnicity are all considered demographic variables.