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. Author manuscript; available in PMC: 2023 Mar 25.
Published in final edited form as: Oncogene. 2022 May 16;41(25):3423–3432. doi: 10.1038/s41388-022-02348-0

Fig. 4. Characterization of P-SCLC developed by Trp53fl/fl;p16fl/fl;Nrf2+/+ and Trp53fl/fl;p16fl/fl;Nrf2E79Q/+ mice.

Fig. 4

a IHC for markers of lung differentiation and for tumor suppressor and NRF2 expression in P-SCLCs from Trp53fl/fl;p16fl/fl;Nrf2+/+ and Trp53fl/fl;p16fl/fl;Nrf2E79Q/+mice,. Images were taken using a BX61-Neville microscope, scalebar=200μm; b IF staining for NE markers of the same tumors. Slides were imaged on the Vectra® Polaris Automated Quantitative Pathology Imaging System, scalebar=100μm.