Table 4.

Overview of deregulated circRNAs in prostate cancer

CircRNA	Expression	Function	Target microRNA	miRNA target genes/protein	Ref
CircPRKCI	Up	Proliferation(+) Metastasis(+)	miR-24-3p	-	[165]
Circ102004	Up	Proliferation(+) Metastasis(+) apoptosis(−)	-	-	[164]
Circ0003258	Up	Metastasis(+)	miR-653-5p	ARHGAP5	[166]
Circ0004296	Down	Proliferation(-) Metastasis(-)	-	EIF4A3/ETS1	[167]
Circ17	Down	Resistance(-)	miRNA-181c-5p	ARv7	[179]
CircTRPS1	Up	Proliferation(+) Metastasis(+)	miR-124-3p	EZH2	[157]
Circ0074032	Up	Proliferation(+) Metastasis(+) Apoptosis(−)	miR-198	HOXA1	[172]
Circ0062019	Up	Proliferation(+) Metastasis(+) Apoptosis(−)	miR-1253	NRBP1	[173]
CircPAPPA	Up	Proliferation(+) Metastasis(+) Apoptosis(−)	miR-515-5p	FKBP1A	[158]
Circ0076305	Up	Metastasis(+) Apoptosis(−)	miR-411-5p	PGK1	[159]
CircSLC19A1	Up	Metastasis(+) Apoptosis(−)	miR-497	SEPT2	[160]
Circ0062020	Down	Metastasis(-) Resistance(-)	miR-615-5p	TRIP13	[168]
CircXIAP	Up	Proliferation(+) Metastasis(+) Apoptosis(−) Resistance(-)	miR-1182	TPD52	[181]
Circ0016068	Up	Metastasis(+)	miR-330-3p	BMI-1	[169]
Circ0088233	Up	Proliferation(+) Metastasis(+) Apoptosis(−)	miR-185-3p	E2F1/WNT2B	[174]
Circ0057558	Up	Proliferation(+)	miR-206	USP33/c-Myc	[161]
Circ0062019	Up	Proliferation(+) Metastasis(+)	miR-195-5p	HMGA2	[162]
Circ0075542	Down	Proliferation(-) Metastasis(-)	miR-1197	HOXC11	[175]
Circ0030586	Up	Proliferation(+) Metastasis(+)	miR-145-3p	-	[170]
CircFMN2	Up	Proliferation(+) Metastasis(+)	miR-1238	LHX2	[163]
Circ0057553	Up	Proliferation(+) Metastasis(+) Apoptosis(−)	miR-515-5p	YES1	[176]
Circ0006404	Up	Proliferation(+) Metastasis(+) Apoptosis(−)	miR-1299	CFL2	[177]
CircDPP4	Up	Proliferation(+) Metastasis(+) Apoptosis(−)	miR-564	ZIC2	[178]
Circ0001686	Up	Proliferation(+) Metastasis(+)	miR-411-5p	SMAD3 /TGFBR2	[171]
Circ0001275	Up	Resistance(+)	-	-	[180]