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. Author manuscript; available in PMC: 2024 Jan 9.
Published in final edited form as: Curr Biol. 2022 Dec 16;33(1):86–97.e10. doi: 10.1016/j.cub.2022.11.042

Figure 6-. Simulation models of population allele frequencies under increasing selection coefficients.

Figure 6-

Simulation models for the frequency of a derived allele (h = 0.75) following 1,440 generations in four populations of Ursus americanus (Nevada: NV; Arizona: AZ; Idaho: ID; and Southeast Alaska: SEAK) connected via gene flow (see Figure S8). Models varied by selection coefficients (s; A- 0; B- 0.005; and C- 0.01), and accounted for population expansion and bottlenecks. Each simulation model was run for 1,000 iterations and panels represent runs in which the derived allele did not go extinct within a run; thus, sample size varies (A- 95; B- 394; and C- 614). Colored points represent R153C genotypic frequencies (circles) estimated in this study for each respective population, or phenotypic frequencies (stars) inferred from contour maps5.