TABLE 1.
Summary statistics for celiac disease patients, reference individuals and siblings.
| Celiac disease | Reference | Siblings | |
|---|---|---|---|
| n [%] | n [%] | n [%] | |
| Total | 45,138 [100.0] | 223,149 [100.0] | 51,449 [100.0] |
| Male | 16,886 [37.4] | 83,177 [37.3] | 26,416 [51.3] |
| Female | 28,252 [62.6] | 139,972 [62.7] | 25,033 [48.7] |
| Age at start follow up | |||
| Mean [SD] years | 32.4 [25.1] | 32.0 [24.9] | 30.8 [21.0] |
| Median [IQR] years | 28.3 [9.1–53.7] | 27.8 [8.9–53.1] | 28.3 [11.7–48.8] |
| <18 years | 17,670 [39.0] | 88,286 [39.6] | 18,480 [35.9] |
| 18 < 40 years | 10,114 [22.4] | 50,235 [22.5] | 14,285 [27.8] |
| 40 < 60 years | 8850 [19.6] | 43,834 [19.6] | 13,260 [25.8] |
| ≥60 years | 8504 [18.9] | 40,794 [18.3] | 5424 [10.5] |
| Years of follow up | |||
| Mean [SD] years | 11.6 [7.1] | 11.8 [7.1] | 11.7 [7.1] |
| Median [IQR] years | 10.9 [5.7–16.9] | 11.0 [5.8–17.1] | 11.0 [5.8–16.9] |
| <1 year | 1568 [3.5] | 5964 [2.7] | 1591 [3.1] |
| 1 < 5 years | 8157 [18.0] | 40,561 [18.3] | 9417 [18.3] |
| 5 < 10 years | 10,893 [24.1] | 53,850 [24.2] | 12,088 [23.5] |
| ≥10 years | 24,520 [54.4] | 122,774 [54.8] | 28,353 [55.1] |
| Year of start follow up | |||
| 1990–2000 | 15,275 [33.8] | 75,656 [33.8] | 16,126 [31.3] |
| 2001–2010 | 20,149 [44.7] | 99,419 [44.6] | 23,595 [45.9] |
| 2011–2016 | 9723 [21.5] | 48,074 [21.6] | 11,728 [22.8] |
| Reason for end of follow‐up | |||
| Emigration | 476 [1.1] | 4292 [1.9] | 588 [1.1] |
| 31 December 2016 | 39,249 [86.9] | 196,612 [88.0] | 47,169 [91.6] |
| Diagnosed with microscopic colitis | 452 [1.0] | 197 [0.09] | 88 [0.2] |
| Diagnosed with lymphocytic colitis | 305 [0.7] | 126 [0.06] | 61 [0.1] |
| Diagnosed with collagenous colitis | 147 [0.3] | 71 [0.03] | 27 [0.05] |
| Death | 4961 [11.0] | 21,444 [9.7] | 2088 [4.0] |
| Diagnosed with celiac disease | 0 [0] | 604 [0.27] | 1516 [2.9] |
| Country of birth | |||
| Nordic | 43,165 [95.4] | 203,881 [91.3] | 50,104 [97.4] |
| Other | 1973 [4.5] | 19,264 [8.7] | 1343 [2.6] |
| Missing | 0 [0.00] | 4 [0.00] | 2 [0.00] |
| Education | |||
| Compulsory school (≤9 years) | 9140 [20.2] | 47,218 [21.2] | 9707 [18.9] |
| Upper secondary school (10–12 years) | 18,121 [40.1] | 92,051 [41.2] | 17,917 [34.9] |
| College or university (≥13 years) | 15,460 [34.2] | 78,699 [35.2] | 11,259 [21.9] |
| Missing | 2417 [5.4] | 5181 [2.3] | 12,566 [24.3] |
| Comorbidity at start of follow up | |||
| Diabetes | 2287 [5.1] | 3515 [1.6] | 965 [1.8] |
| Inflammatory bowel disease | 1107 [2.5] | 356 [0.2] | 418 [0.8] |
| Thyroid disease | 963 [2.2] | 1598 [0.7] | 477 [0.9] |
| Rheumatoid arthritis | 333 [0.7] | 944 [0.4] | 262 [0.5] |