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. 2023 Jan 19;60(5):2426–2441. doi: 10.1007/s12035-023-03224-y

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Identification of significantly altered miRNAs in brain from AD patients. A Relative expression levels of top 17 miRNAs from control and Alzheimer’s disease (AD) subjects. For each miRNA, left column represents the control and the right column represents the AD. Unpaired t-test, p-value showed on the top of each group. B–D Relative expression levels of matured miR-650 (B), primary miR-650 (C), and precursor and primary transcript of miR-650 (D) for control and AD subjects. Unpaired t-test, p < 0.01. Control, n = 16; AD, n = 18