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. 2023 Mar 25;6:323. doi: 10.1038/s42003-023-04693-6

Fig. 5. Bay117082 promotes sperm motility independently of glucose metabolism.

Fig. 5

a, b Changes in VCL and ALH of sperm treated with 25 μM Bay117082 in BWW-GPL or BWW media for 10 and 30 mins. BWW-GPL: BWW media lacking glucose (G), pyruvate (P) and lactic acid (L). Values represent mean ± SEM (n = 7), *p < 0.05, **p < 0.01, ***p < 0.001, as compared with the corresponding control (0 μM) in each medium. c Changes in motile percent of sperm incubated with 500 μM α-chlorohydrin (ACH) for 1 h. Values represent mean ± SEM (n = 7), **p < 0.01. d Changes in VCL of sperm treated with 25 μM Bay117082 in the absence or presence of 500 μM ACH for 1 h. Values represent mean ± SEM (n = 7), ***p < 0.001, as compared with the corresponding control.