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. 2023 Mar 25;14:1677. doi: 10.1038/s41467-023-37092-w

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© The Author(s) 2023, corrected publication 2023

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Fig. 7 — Consideration of clinical features and histopathology together with the identification of a DICER1 hotspot pathogenic variant is usually sufficient to classify DICER1-associated mesenchymal neoplasms. However, in diagnostically challenging cases ancillary molecular studies may aid tumor classification. Diagnosis of a mesenchymal tumor with DICER1 alteration should always promt germline testing for DICER1 syndrome.