Table 1.
Individual models association with functional connectivity parameters
Individual models | |||||||||
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Callous-Unemotional traits | Cognitive empathy | Affective empathy | |||||||
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Outcomes | β | q | R2 | β | q | R2 | β | q | R2 |
DMN | −0.005* | 0.038 | 0.140 | 0.008* | 0.015 | 0.119 | 0.008 | 0.057 | 0.122 |
FPN | −0.001 | 0.969 | 0.001 | 0.001 | 0.927 | 0.016 | 0.000 | 0.972 | 0.076 |
SAL | −0.002 | 0.694 | 0.036 | 0.002 | 0.709 | 0.002 | 0.009 | 0.082 | 0.001 |
DMN-FPN | −0.003 | 0.136 | 0.124 | 0.001 | 0.659 | 0.062 | 0.000 | 0.694 | 0.062 |
DMN-SAL | 0.004* | 0.002 | 0.132 | −0.007* | 0.006 | 0.129 | −0.008* | 0.003 | 0.136 |
FPN-SAL | 0.003 | 0.152 | 0.669 | 0.002 | 0.627 | 0.015 | −0.005 | 0.440 | 0.042 |
Note: all path models adjusted for sex and pubertal development, callous-unemotional traits model additionally adjusted for conduct problems.
DMN= default mode network, SAL= salience network; Network abbreviations separated by a hyphen indicate between network connectivity whereas standalone abbreviations indicate within network.
Predictor at the top was a separate path model estimates on the multiple outcomes in the left column.
See Supplementary Figure 1 for depiction of all models ran.
q= FDR corrected p value
q < 0.05