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. 2023 Mar 15;42(2):289-295. doi: 10.5937/jomb0-40379

Table 4. Serum markers of fibrosis damage.

Note: Compared to controls, aP< 0.05; compared to diabetes group, bP<0.05; compared to mild DN group, cP<0.05.

Groups TGF-β (μg/L) HA (μg/L) CIV (μg/L) PCIII (μg/L)
Controls 5.28±0.8 30.85±4.69 41.29±6.33 23.69±2.69
Diabetes 8.25±0.91a 42.68±5.24a 59.14±6.85a 32.75±3.22a
Mild DN 12.24±1.36ab 58.33±6.96ab 67.32±7.17ab 44.23±4.16ab
Moderate-severe DN 15.21±1.98abc 78.91±9.51abc 89.53±9.24abc 55.98±5.96abc
F 621.003 524.517 280.321 646.206
P <0.001 <0.001 <0.001 <0.001