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. 2015 Sep 21;2015(9):CD006362. doi: 10.1002/14651858.CD006362.pub4

Comparison 2. NSAIDs versus placebo, analgesic effect.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Throat irritation score (fixed‐effect model) 2 159 Std. Mean Difference (IV, Fixed, 95% CI) ‐0.01 [‐0.33, 0.30]
2 Headache score (random‐effects model) 2 159 Std. Mean Difference (IV, Random, 95% CI) ‐0.65 [‐1.11, ‐0.19]
3 Score of pain in muscles/joints score (fixed‐effect model) 2 114 Std. Mean Difference (IV, Fixed, 95% CI) ‐0.40 [‐0.77, ‐0.03]
4 Malaise score (fixed‐effect model) 2 159 Std. Mean Difference (IV, Fixed, 95% CI) ‐0.29 [‐0.60, 0.03]
5 Chilliness score (random‐effects model) 2 159 Std. Mean Difference (IV, Random, 95% CI) ‐0.03 [‐1.12, 1.06]
6 Nose irritation score 1 80 Std. Mean Difference (IV, Fixed, 95% CI) ‐0.04 [‐0.48, 0.40]
7 Score of pain on swallowing 1 80 Std. Mean Difference (IV, Fixed, 95% CI) ‐0.07 [‐0.51, 0.37]
8 Eye itching score 1 80 Std. Mean Difference (IV, Fixed, 95% CI) ‐0.14 [‐0.58, 0.30]
9 Earache score 1 80 Std. Mean Difference (IV, Fixed, 95% CI) ‐0.59 [‐1.04, ‐0.14]