. Author manuscript; available in PMC: 2023 Mar 26.

Published in final edited form as: Sci Transl Med. 2017 Aug 30;9(405):eaan1240. doi: 10.1126/scitranslmed.aan1240

Table 4. Clinical outcome data for cohort 2 cases with RATs.

Misc., miscarriage; MCA, multiple congenital abnormalities; NLB, normal live birth; NA, follow-up not available; Mat, maternal; Av., average; TF, trisomic fraction; FF, fetal fraction.

	Missed or early misc.	TFM	UPD	IUFD	IUGR	MCA	NLB	NA	Mat	Total
Trisomy 2		3	(2^*)	1	(1^*, 1^†)		1			5
Trisomy 3							1	1		2
Trisomy 4			2	1						3
Trisomy 5								1		1
Trisomy 7		1			(1^*)		5	3		9
Trisomy 8							1	1	1	3
Trisomy 9	1				1	1	1			4
Trisomy 10	1						2			3
Trisomy 14	1									1
Trisomy 15	13		1							14
Trisomy 16	2	1	2	(2^‡)	(1^‡)		2			7
Trisomy 20	1				1			1		3
Trisomy 22	3	1^§					1	1		5
Total	22	5 (+1^§)	5 (+2^*)	2 (+2^‡)	2 (+4^*^†‡)	1	14	8	1	60
Av. TF	7.60	8.55	9.90	7.23	7.83	4.65	5.52	3.84	14.05
Av. FF	7.15	8.32	8.82	6.98	7.52	4.45	8.97	8.81	11.08
Ratio Av. TF:FF	1.06	1.03	1.12	1.04	1.04	1.04	0.62	0.44	1.27

Also recorded as TFM.

^†

Also recorded as IUFD.

^‡

Also recorded as UPD.

^§

Also recorded as miscarriage.