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. Author manuscript; available in PMC: 2023 Mar 26.
Published in final edited form as: Prenat Diagn. 2020 Dec;40(13):1636–1640. doi: 10.1002/pd.5871

TABLE 1.

Trends in MeSH terms over time

Topic 1980–1984 1985–1989 1990–1994 1995–1999 2000–2004 2005–2009 2010–2014 2015–2019
Prenatal Cytogenetics 94% 87% 91% 71% 60% 55% 39% 31%
Congenital Anomalies 45% 38% 47% 37% 46% 49% 39% 41%
Fetal Imaging 22% 22% 24% 29% 33% 35% 30% 18%
Single gene disorders 29% 30% 28% 19% 16% 14% 9% 8%
Serum Screening 11% 12% 22% 20% 15% 14% 14% 14%
Molecular Genetics 2% 8% 11% 15% 14% 16% 15% 19%
Blood 15% 10% 6% 10% 7% 7% 4% 2%
Maternal Health 1% 4% 3% 4% 4% 8% 12% 4%
Multiple Gestation 8% 3% 7% 4% 4% 9% 7% 4%
Placenta 3% 5% 6% 5% 4% 5% 8% 5%
Sex Chromosomes 6% 6% 6% 6% 6% 7% 3% 3%
NIPT 0% 0% 0% 0% 0% 2% 7% 18%
Fetal Therapy 9% 1% 0% 2% 1% 3% 7% 7%
Health Attitudes 1% 1% 2% 2% 3% 5% 6% 4%
Abortion 5% 5% 5% 2% 3% 5% 4% 3%
Genetic Counseling 2% 2% 2% 1% 5% 4% 4% 4%
Preimplantation Genetic Testing 0% 1% 1% 2% 8% 5% 2% 2%
Growth Restriction 1% 2% 2% 2% 3% 3% 5% 3%
Neoplasms 5% 3% 5% 2% 3% 2% 2% 1%
Infection 0% 1% 3% 3% 2% 2% 2% 1%
Enzyme 15% 9% 4% 2% 2% 0% 0% 0%

The deepest shade of green is the highest value.

The lightest shade of green is the lowest value.

The midpoint is at the 70%.