. Author manuscript; available in PMC: 2023 Mar 26.

Published in final edited form as: Clin Transplant. 2021 Feb 6;35(3):e14206. doi: 10.1111/ctr.14206

TABLE 2.

Inflammatory and angiogenesis markers

pg/ml	High dd-cfDNA (≥0.12%, n=32)	Low dd-cfDNA (<0.12%, n=26)	p-value
IL-6	1.22 (0.29, 1.70)	0.85 (0, 1.89)	.74
IL-18	24.98 (19.15, 40.53)	34.47 (27.17, 48.10)	.049^*
TNF-a	1.91 (1.44, 2.87)	2.26 (1.22, 2.68)	.84
sFASL	24.01 (12.08, 76.49)	69.76 (18.87, 91.34)	.066
Ang-2	350.31 (123.10, 659.18)	480.61 (274.96, 869.39)	.075
VEGF-A	58.05 (41.16, 76.66)	75.61 (49.83, 98.65)	.13
VEGF-C	154.97 (109.74, 376.44)	283.85 (151.58, 462.97)	.123
VEGF-D	79.02 (53.42, 178.47)	155.71 (84.27, 176.70)	.12
TGFa	3.11 (2.43, 8.83)	5.09 (3.42, 9.92)	.29

Abbreviations: Ang-2, Angiopoetin-2; dd-cfDNA, Donor-derived Cell-free DNA; IL-18,

Interluekin-18; IL-6, Interluekin-6; sFASL, Soluble Fas-ligand; TGF-α, Transforming growth factor-alpha; TNF-α, Tumor necrosis factor-alpha; VEGF, Vascular endothelial growth factor A, C and D.

p < .05.