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Assay cutoff, sensitivity, and specificity for GADA, IA-2A, ZnT8A, IAA, and TGA among 880 ASK samples, including 325 IAbs positive samples and 555 all antibodies negative samples.
| Cut-off index value | Sensitivity | Specificity | |
|---|---|---|---|
| GADA | 0.01 | 81% | 99% |
| IA-2A | 0.007 | 89% | 99% |
| ZnT8A | 0.007 | 83% | 99% |
| IAA | 0.006 | 69% | 99% |
| TGA | 0.008 | 96% | 100% |
The optimal cutoff index value of GADA, IA-2A, ZnT8A, IAA, and TGA assay was set to at least the 99th percentile of the 555 normal control samples.
