Table 3.
Antibody response to COVID-19 vaccine in all-volunteer women.a
| D Group (n=16) | C Group (n=17) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| W1 | W2 | W3 | pb | pc | pd | W1 | W2 | W3 | pe | pf | p7 | p8 | |
| IgG (COI) | 3.36 (0.34) | 4.51 (0.12) | 3.91 (0.31) | <0.001 | 0.001 | 0.004 | 3.94 (0.43) | 3.86 (0.81) | 3.78 (0.61) | 0.779 | <0.001 | 0.001 | 1.000 |
| 25 (OH) D (ng/mL) | 10.97 (2.41) | 14.37 (4.63) | 27.18 (12.08) | 0.021 | <0.001 | 0.001 | 12.60 (4.10) | 12.20 (3.77) | 14.78 (10.75) | 0.646 | 0.121 | 0.036 | <0.001 |
| Pre-Study Values of Volunteers experiencing COVID-19 Disease | |||
| D Group (n=6) | C Group (n=6) | pi | |
| IgG (COI) | 3.53 (0.45) | 3.98 (0.31) | 0.078 |
| 25(OH) D (ng/mL) | 11.05 (1.39) | 13.90 (6.28) | 0.575 |
| The time between antibody measurement and the disease (days) | 353.50 (80.02) | 242.00 (177.79) | 0.423 |
D group, Vit-D supplemented group; C group, No supplemented group. Immunoglobulin G: IgG, Immunoglobulin M: IgM, 25-Hydroxy(25(OH)) vitamin D: 25(OH) D,
aAb titers are expressed as mean ± SD.
b, c, d Determined using a paired Wilcoxon test for intra-group differences between Antibody titers in the D group (W1-W2 (pb)), (W2-W3 (pc)), and (W1-W3 (pd)).
eDetermined using Friedman test for intra-group differences between Antibody titers in the C group (pe).
e,f,g,h Determined using Mann-Whitney U-test for inter-group differences in W1-W1 Antibody titers (pf), W2-W2 Antibody titers (pg), and W3-W3 Antibody titers (ph) between D and C groups.
ip-values were determined using a Mann-Whitney U-test.