REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Mouse anti-human IFN-γ monoclonal antibody	BD Pharmigen	Cat # 554699; RRID: AB_2313773
Rabbit polyclonal anti-human IFN-γ Biotin	U-Cytech	Cat # CT243; RRID: AB_2313773
Streptavidin-alkaline phosphatase antibody	Southern Biotech	Cat # 7100-04; RRID: AB_2313773
Anti-macaque IgG HRP	Nonhuman Primate Reagent Resource	Cat# 1b3-HRP: 0320K235 / 070920SC; RRID: AB_2313773
Mouse anti-human CD45 BUV805	BD Pharmingen	Cat # 742055 RRID:AB_2871344
Mouse anti-human CD11c Alexa700	Affymetrix	Cat # 56-0116-42 RRID:AB_10547281
Mouse anti-human CD123 Alexa700	FISHER/NOVUS	Cat # NB6001185AF700; RRID: AB_2313773
Mouse anti-human CD7 Alexa700	BD Pharmingen	Cat # 561603 RRID:AB_10898348
Mouse anti-human CD3 APC-Cy7	BD Pharmingen	Cat # 557757 RRID:AB_396863
Mouse anti-human CD14 BV570	BIOLEGEND	Cat # 301832 RRID:AB_2563629
Mouse anti-human CD21 BV605	BD Pharmingen	Cat # 740395 RRID:AB_2740125
Mouse anti-human CD95 BV711	BIOLEGEND	Cat # 305644 RRID:AB_2632623
Mouse anti-human CD80 BV786	BD Pharmingen	Cat # 564159 RRID:AB_2738631
Mouse anti-human IgM BUV395	BD Pharmingen	Cat # 563903 RRID:AB_2721269
Mouse anti-human CD27 BUV563	BD Pharmingen	Cat # 741366 RRID:AB_2870866
Mouse anti-human IgG BUV737	BD Pharmingen	Cat # 612819 RRID:AB_2870143
Goat anti-human IgD PE	Southern Biotec	Cat # 2030-09 RRID:AB_2795630
Mouse Anti-Bcl-6 PE-CF594	BD Pharmingen	Cat # 562401; RRID: AB_2313773
SARS CoV Nucleoprotein / NP mouse monoclonal antibody (Clone MM05)	Sino Biological	Cat # 40143-MM05 RRID:AB_2827977
Biological samples
Non-human primate SARS-CoV2 infected lung tissue	Bioqual, Inc.	N/A
Bronchoalveolar lavage from Non-Human Primates	Bioqual, Inc.	N/A
Nasal swabs from Non-Human Primates	Bioqual, Inc.	N/A
EDTA, SST, Paxgene collection tubes with whole blood, from Non-Human Primates	Bioqual, Inc.	N/A
Chemicals, peptides, and recombinant proteins
Peptides for WA1/2020, Omicron, Delta, Beta	21st Century Biochemicals	Custom
Nitroblue Tetrazolium Chloride/5-bromo-4-chloro 3 ‘indolyl phosphate p-toludine salt	Thermo Scientific	Cat #34042
SARS-CoV-2 Receptor Binding Domain protein (WA1/2020, Omicron, Delta, Beta)	Aaron Schmidt Laboratory; Harvard Medical School	https://doi.org/10.1126/sciimmunol.abe0367
Biotinylated SARS-CoV-2 (WA1/2020) RBD	Sino Biological	Cat # 40592-V08B-B
SARS-CoV-2 (WA1/2020) RBD	Sino Biological	Cat # 40592-V08B
SARS-CoV-2 (Omicron) RBD	Sino Biological	Cat # 40592-V08H121
BV650 streptavidin	BD Pharmingen	Cat # 563855 RRID:AB_2869528
Fixation Medium (Medium A)	ThermoFisher Scientific	Cat # GAS001S100
Permeabilization Medium (Medium B)	ThermoFisher Scientific	Cat # GAS002S100
Citrate buffer antigen retrieval	ThermoFischer Scientific	Cat # AP-9003-500
Protein block	Biocare	Cat # BP974M
DaVinci Green Antibody diluent	Biocare	Cat # PD900M
Mach-2 Mouse HRP-Polymer	Biocare	Cat # MHRP520L
Critical commercial assays
V-PLEX SARS-CoV-2 Panel 22 Kit – Human IgG	Meso Scale Discovery	K15559U
V-PLEX SARS-CoV-2 Panel 23 Kit – Human IgG	Meso Scale Discovery	K15567U
Experimental models: Cell lines
HEK293T-hACE2	This paper	N/A
Experimental models: Organisms/strains
Macaca mulatta	This paper	N/A
Oligonucleotides
Primer:sgLeadSARSCoV2-F Forward: CGATCTCTTGTAGATCTGTTCTC	Wolfel et al., 2020	ThermoFisher Scientific:4448510
Primer: E_Sarbeco_R Reverse: ATATTGCAGCAGTACGCACACA	Wolfel et al., 2020	ThermoFisher Scientific:4448510
Probe:E_Sarbeco_P1 : VIC-ACACT AGCCATCCTTACTGCGCTTCG-MGBNFQ	Wolfel et al., 2020	ThermoFisher Scientific:4448510
Primer:pcDNA.T7.NdeI.Fwd Forward: TGATCTCATATGGAACCCACTGCTTACTG	This paper	Integrated DNA Technologies
Primer: pcDNA.T7.Rev Reverse: CACTGTGCTGGATATCTGC	This paper	Integrated DNA Technologies
Recombinant DNA
psPAX2	AIDS Resource and Reagent Program	Cat# 11348
pLenti-CMV Puro-Luc	Addgene	Cat# 17477
pcDNA3.1-SARS CoV-2 SΔCT	This paper	N/A
Software and algorithms
GraphPad Prism 8.4.2	GraphPad Software	http://www.graphpad.com/scientific-software/prism/
FlowJo	BD Bioscience	http://www.flowjo.com/
Diva SoftMax Pro 6.5.1	SoftMax Pro Software	www.moleculardevices.com/products/microplate-readers/acquisition-and-analysis-software/softmax-pro-software
BioRender	BioRender	https://biorender.com/
Other
Ad26.COV2.S	Janssen	JNJ-78436735
SpFN	WRAIR	N/A
RNA Standard: SARS-CoV-2 E gene subgenomic RNA (sgRNA)	This paper	N/A