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. 2023 Mar 7;4(3):100957. doi: 10.1016/j.xcrm.2023.100957

Figure 7.

Figure 7

KCC2 activation reduces neuronal cell death 48 h after BDZ-RSE

(A) Mice that survived for 48 h following KA-induced seizures were sacrificed, and brain sections were subjected to TUNEL/DAPI staining followed by confocal microscopy. The righthand panels (scale bar: 50 μm) are enlargements of the boxed areas in the lefthand panels (scale bar: 1 mm).

(B) The number of TUNEL+ neurons was quantified in hippocampal slices from both treatment groups (n = 18 and 22 slices for DZ and DZ/350, respectively).

(C) The number TUNEL+ neurons was quantified in mice from both treatment groups (n = 4 and 5 mice for DZ and DZ/350, respectively).

In all panels, p values were determined using t tests, ∗p < 0.05.