Comparative targeted whole-exome sequencing analysis of pediatric and adult acute myeloid leukemia samples
(A) Study design schematic.
(B) Targeted whole-exome (next-generation) sequencing analysis of 124 hematopoietic malignancy-associated genes was performed on DNA extracted from peripheral blood or bone marrow mononuclear cells isolated from pediatric AML (pAML, n = 11) patients and adult de novo AML (dnAML, n = 3) patients. See also Figure S1.