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. 2023 Mar 1;40(5-6):561–577. doi: 10.1089/neu.2022.0282

Table 1.

Summary of Differentially Expressed Genes at 6 Weeks and 12 Months Post-Blast Exposure

Time post-blast Area Total DEGs DEGs up DEGs down
6 weeks Amygdala 8 Col5a1, C3, Rpl21, Fance Gad2, Tac1, Nxph, Ahi1
6 weeks Anterior cortex 3 Tsc22d4 Fundc2, AC134224.3
6 weeks Hippocampus 0 0 0
6 weeks Cerebellum 22 Wdr66, Ak5, LOC100365697, AABR07053509.2, Chd7, Camk1g, Gria2, Plekha5, Cemip, Pigk, Zfhx2, Kcnb1, Crebbp, Myt1, Per3 Cam2k, Fundc2, Col9a2, Mras, Rpl12, Comtdi, Prdx2.
12 months Amygdala 17 Hapln4, ATP6v0c AABR07015057.1, AABR07063425.2
Mast2, Agpat3, AABR07015079, Chd3, Abcd3, Ttbk1, Mobp, Tmem151b, Cbx6, Csnk1g2
AABR07015081.1,
AABR07015081.2, AC134224.1
12 months Anterior cortex 0 0 0
12 months Hippocampus 1 0 Map3k7
12 months Cerebellum 2 Aurkb, Mmp14 0

DEGs, differentially expressed genes; Col5a1, collagen alpha-1(V); Rpl21, ribosomal protein L2; Fance, FA complementation group E; Tsc22d4, TSC22 domain family member 4; Wdr66, WD repeat-containing protein 66; Ak5, adenylate kinase 5; Chd7, chromodomain-helicase-DNA-binding protein 7; Camk1g, calcium/calmodulin dependent protein kinase IG; Gria2, glutamate ionotropic receptor AMPA type subunit 2; Plekha5, pleckstrin homology domain containing A5; Cemip, cell migration inducing hyaluronidase 1; Pigk, phosphatidylinositol glycan anchor biosynthesis class K; Zfhx2, zinc finger homeobox 2; Kcnb1, potassium voltage gated channel subfamily b member 1; Crebbp, cyclic adenosine monophosphate response element binding protein; Myt1, myelin transcription factor 1; Per3, period circadian regulator 3; Hapln4, hyaluronan and proteoglycan link protein 4; ATP6v0c, ATPase H+ transporting V0 subunit C; Aurkb, aurora kinase B; Mmp14, matrix metallopeptidase 14; Gad2, glutamate decarboxylase 2; Tac1, tachykinin precursor 1; Nxph, neurexophilin 1; Ahi1, abelson helper integration site 1; Fundc2, FUN14 domain containing 2; Cam2k, calcium/calmodulin-dependent protein kinase type II; Col9a2, collagen type IX alpha 2 chain; Mras, muscle RAS oncogene homolog; Rpl12, ribosomal protein L12; Comtd1, catechol-o-methyltransferase domain containing 1; Prdx2; peroxiredoxin 2; Mast2, microtubule associated serine/threonine kinase 2; Agpat3, 1-acylglycerol-3-phosphate o-acyltransferase 3; Chd3, chromodomain-helicase-DNA-binding protein 3; Abcd3, ATP binding cassette subfamily D member 3; Ttbk1, tau tubulin kinase 1; Mobp, myelin associated oligodendrocyte basic protein; Tmem151b, transmembrane protein 151B; Cbx6, chromobox 6; Csnk1g2, casein kinase 1 gamma 2; Map3k7, mitogen-activated protein kinase kinase kinase 7.