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. Author manuscript; available in PMC: 2023 Mar 27.
Published in final edited form as: Nat Biomed Eng. 2023 Feb 6;7(3):270–280. doi: 10.1038/s41551-023-01003-7

Table 1 |.

Physicochemical properties of ZW800-1A and ZW800-1C

Fluorophore ZW800-1A ZW800-1C
Molecular weight (Da) 944.24 928.24
Charges (+/−) +3/−3 +3/−3
LogP −0.61 −0.24
LogD, pH 7.4 −3.35 −2.80
TPSA (Å2) 167.18 157.95
HBA/HBD 10/1 8/1
Rotatable bonds 18 17

LogP, partition coefficient; logD, distribution coefficient; TPSA, topological polar surface area; HBA, hydrogen bond acceptors; HBD, hydrogen bond donors.