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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Laryngoscope. 2022 Sep 27;133(8):1899–1905. doi: 10.1002/lary.30419

TABLE III.

SEER 2000 Staging and Treatment per Primary Site of Oral Cavity or Pharyngeal Malignancy.

Staging SEER 2000 stagea Buccal Mucosa Tongue Lip
USAPI (51) US (3633) USAPI (44) US (20211) USAPI30 US (7812)
1 14 (27.5%) 2061 (56.7%) 15 (34.1%) 12902 (63.8%) 11 (36.7%) 7247 (92.8%)
p-valueb <0.001 <0.001 <0.001
2 9 (17.6%) 201 (5.5%) 2 (4.5%) 859 (4.3%) 2 (6.67%) 164 (2.1%)
p-value <0.001 0.78 0.27
3 2 (3.9%) 435 (12.0%) 4 (9.1%) 3538 (17.5%) 9 (30.0%) 217 (2.8%)
p-value 0.12 0.20 <0.001
4 7 (13.1%) 133 (3.7%) 14 (31.8%) 1210 (6.0%) 8 (26.7%) 49 (0.6%)
p-value <0.001 <0.001 <0.001
5 10 (19.6%) 0 (0.0%) 6 (13.6%) 3 (0.01 %) 0 1 (0.01%)
p-value < 0.001 <0.001 0.95
7 9 (17.6%) 803 (22.1%) 3 (6.8%) 1699 (8.4%) 0 134 (1.7%)
p-value 0.55 0.91 0.99
a

Chi-squared tests for independence were conducted between the US-associated Pacific Island (USAPI) and SEER (US) cohorts.

b

p-values from Chi-squared tests for independence with Yates correction for entries <10 with an α = 0.0028 after Bonferroni correction.