Table 3.

Secondary Outcomes

	Original Cohort				Weighted Cohort
	≤1000 mg/day (n=289)	1500 mg/day (n=137)	≥2000 mg/day (n=440)	Total (N=866)	≤1000 mg/day (n=193)	1500 mg/day (n=133)	≥2000 mg/day (n=225)	Total (N=551)
Early PTS	9 (3.1%)	9 (6.6%)	33 (7.5%)	51 (5.9%)	4 (2.3%)	9 (7%)	16 (7.3%)	30 (5.5%)
Time to seizure, hours (SD)	45.9 (29.4)	72.6 (44.8)	57.3 (44.9)	58 (42.6)	42.6 (6.7)	76.6 (16.7)	66.9 (12.7)	66.4 (8.8)
Seizure validation
EEG	3 (33.3%)	7 (77.8%)	23 (69.7%)	33 (64.7%)	1 (24.8%)	7 (80.3%)	13 (79.3%)	22 (71.7%)
Clinical diagnosis	6 (66.7%)	2 (22.2%)	10 (30.3%)	18 (35.3%)	3 (75.2%)	2 (19.7%)	3 (20.7%)	8 (28.3%)
Death without seizure	12 (4.2%)	7 (5.1%)	35 (8%)	54 (6.2%)	6 (2.9%)	7 (5%)	16 (7.2%)	28 (5.1%)
In-hospital mortality	19 (6.6%)	13 (9.5%)	74 (16.8%)	106 (12.2%)	10 (5.2%)	12 (9.2%)	37 (16.4%)	59 (10.7%)
Hospital LOS, days (IQR)	5 (3, 10)	6 (3, 11)	9.5 (4, 23)	7 (3, 17)	5.5 (2.2, 13.7)	5.8 (2.4, 11.1)	6.1 (2.5, 16.4)	5.8 (2.4, 14.1)

Data are presented as mean (SD), median (IQR), or n (%)

PTS: Post-traumatic seizures. SD: Standard deviation. EEG: Electroencephalogram. LOS: Length of stay. IQR: Interquartile range.