Table 3.
Protein and peptide drugs.
| Biological inhibitor | Inhibition mechanism | Refs. |
|---|---|---|
| DsbA-L | Interaction with Ero1-L; Promote AMPK phosphorylation | (164, 165) |
| SIRT2 | Deacetylation of NLRP3 | (166) |
| HIF2α | Promotion of H3K27me3 modification and inhibition of CPT1A expression | (167) |
| CWA | Regulate the expression of TXNIP and the activation of p65 | (168) |