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. 2023 Mar 13;14:1052756. doi: 10.3389/fimmu.2023.1052756

Table 3.

Protein and peptide drugs.

Biological inhibitor Inhibition mechanism Refs.
DsbA-L Interaction with Ero1-L; Promote AMPK phosphorylation (164, 165)
SIRT2 Deacetylation of NLRP3 (166)
HIF2α Promotion of H3K27me3 modification and inhibition of CPT1A expression (167)
CWA Regulate the expression of TXNIP and the activation of p65 (168)