Table 1.

Comparison of the main parameters, namely bronchoalveolar lavage (BAL) total leukocyte counts (TLC), BAL viability, BAL protein, BAL chemokines, lung vascular perfusate TLC, perfusate chemokines, peripheral blood TLC, lung myeloperoxidase (MPO) and lung eosinophil peroxidase (EPX).

Parameter	Control	Vehicle	Anti-CD61 Ab	BTB06584	Propranolol	Dexamethasone
BAL TLC	+	+	+++++	+++	+++	+++
BAL Viability	++++++	+	+	++++++	++++	++++
BAL Protein	+	+	++++++	++++++	+	++
BAL Chemokines	CCL-27, IL-10	High but not significant: CXCL5	Highest ↑: CXCL13, CXCL5, KC, MCP-1, MCP-3, MDC, MIP-1a, MIP-1b, MIP-2, MIP-3a, RANTES, TARC Moderate ↑: IL-16	Highest ↑: IL-16, RANTES Moderate: CXCL13, CXCL5, eotaxin-2, IL-6, MIP-1a, MIP-1b, MIP-2, MIP-3a	Moderate ↑: CXCL13, CXCL5, MIP-1b, TARC	Highest ↑: eotaxin-2, IL-6, MIP-1a, MIP-1b, MIP-2, CXCL16 Moderate ↑: CXCL13, CXCL5, IL-16, MIP-3a, RANTES
Perfusate TLC	++++++	+	+	+	+	+
Perfusate Chemokines		Moderate ↑: CXCL5, SDF-1α, CXCL13	Highest ↑: CXCL5, SDF-1α, CXCL13	Highest ↑: CXCL13 Moderate ↑: CXCL5, SDF-1α	Moderate ↑: CXCL5, SDF-1α, CXCL13, TECK	Moderate ↑: SDF-1α, CXCL13
Peripheral Blood TLC	++++++	+	+	+	+	+
Lung MPO	+	++++++	+	++	++	+
Lung EPX	+	++++++	+	++	++++	+

The symbols + to ++++ stand for the graded magnitude of the observed parameter in each group with + being the least and ++++ being the maximum. The symbol ↑ stands for an increase in the parameter described.