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Gene Set Enrichment Analysis (GSEA) reveals cellular pathways modified by PHX on M1 macrophages. GSEA of 2999 proteins derived from vehicle or 5 μM treated M1 macrophages using the Molecular Signatures Database (MSigDB) Hallmark data set. (A) Enrichment Score (ES) plots of statistically significant enriched Hallmark data gene sets. (B) Heatmap identifying protein expression associated with each Hallmark gene set.
