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. 2023 Mar 13;13:1154346. doi: 10.3389/fcimb.2023.1154346

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Copyright © 2023 Pan, Pei, Fang, Wang, Zhu, Zhang, Zhao, Chen and Lu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The heatmap represents the correlation between the number of genes and the concentration of metabolites, and the statistical significance will be marked only when Spearman’s ρ (Benjamin Hochberg false discovery rate [FDR]) is greater than 0.3.***p = 0.0003, ****p < 0.0001. (B) Phylogenetic trees were built using the indolelactate dehydrogenase (fldH) homologous sequences of all lactic acid bacteria. Without modifying the topological structure of phylogenetic trees, the folded branches were used to facilitate the display of two different types of fldH sequences of L. salivarius. The folded cluster of fldH from L. salivarius was marked blue.