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. 2023 Mar 13;14:1112816. doi: 10.3389/fimmu.2023.1112816

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Copyright © 2023 Tan, Zhu, Pan, Wu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Vaccine candidates (MPXV-2 and MPXV-5) docked with TLR2 and TLR4. (A) The binding mode between the MPXV-2 and TLR2 and the interacting residues of the MPXV-2 with TLR2; (B)The binding mode between the MPXV-2 and TLR4 and the interacting residues of the MPXV-2 with TLR4; (C) The binding mode between the MPXV-5 and TLR2 and the interacting residues of the MPXV-5 with TLR2; (D) The binding mode between the MPXV-5 and TLR4 and the interacting residues of the MPXV-5 with TLR4.