Average performance of benchmark models when being tested on all tumor indications. Matrix entry mi,j is the average precision (AP) when training on the indication in row i and testing on the indication in column j. Diagonal elements indicate in-domain performance, whereas off-diagonal elements represent cross-domain performance. HNSCC: head and neck squamous cell carcinoma, NSCLC: non-small cell lung cancer, TNBC: triple-negative breast cancer, GC: gastric cancer.