Table 2.
Participant's characteristics and stimulation parameters of studies assessing nVNS in rarer primary headaches.
| Author (reference) | Year | Diagnosis (N) | Type of study | Female % | Age (SD) | Duration of stimulation | Stimulation parameters | Stimulation details |
|---|---|---|---|---|---|---|---|---|
| Nesbitt et al (52) | 2013 | HC (2) | Open Label | 50% | 56–61 | 24–32 weeks | NR | NR |
| Eren et al (53) | 2016 | HC (1) | Open Label | 0% | 58 | 4 weeks | Maximum 24 V and 60 mA DC sine wave series of 5kHz for 1 ms, repeated every 40 ms (25 Hz) | AA: patient reached maximum level 40/40 |
| Tso et al (51) | 2017 | HC (9), PH (6) | Retrospective | 73.30% | 42.9 | 3 months to 5 years | NR | |
| Trimboli et al (49) | 2018 | RTT CM (23), CCH (12), HC (4), SUNA (2) | Open Label | 54% | 44 (median) | > 3 months | AA. Training provided | |
| Kamourieh et al (54) | 2019 | CPH (8) | Retrospective | 37.50% | 48 | 3–19 months | AA, MC, Training provided and technique reviewed | |
| Moreno-Ajona et al (55) | 2021 | PCH (1) | Open Label | 0% | 53 | >3 months | AA, MC, Training provided and technique reviewed |