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. 2023 Mar 13;14:1126129. doi: 10.3389/fendo.2023.1126129

Table 2.

Participants’ characteristics of included studies.

Author Year leptin R NOS
Case Control
Arumugam R(male) 1998 2.2±1.4 ng/mL 3.4±1.2 ng/mL 5
Arumugam R(female) 1998 7.1±4.1 ng/mL 5.4±3.7 ng/mL 5
Ahme ML (male) 2004 1.07±0.49 ng/mL 1.02±0.5 ng/mL R1= 0.45 5
Ahme ML (femle) 2004 2.11±0.86 ng/mL 1.34±0.44 ng/mL R1= 0.28 5
Schmitt-Grohe S(mild) 2006 5.22±6.82 pg/mL 6.78±9.9 pg/mL R2= 0.351 8
Schmitt-GroheS(moderate) 2006 6.96±11 pg/mL 6.78±9.9 pg/mL R2= 0.351 8
Stylianou C(male) 2006 11.27±1.54 ng/mL 8.78±5.59 ng/mL 7
Stylianou C(female) 2006 21.57±7.68 ng/mL 14.89±5.71 ng/mL 7
Boguszewski MC (male) 2007 2.07±0.79 ng/mL 3.07±1.28 ng/mL R1= 0.6 4
Boguszewski MC (female) 2007 2.71±0.86 ng/mL 5±2.95 ng/mL R1= 0.6 4
Cohen RI (mild) 2008 8.4±1.8 pg/mL 8.2±2 pg/mL R1=0.56; R2=0.4; R3=0.34 7
Cohen RI (moderate) 2008 8.1±1.7 pg/mL 8.2±2 pg/mL 7
Cohen RI (severe) 2008 2.4±2 pg/mL 8.2±2 pg/mL 7
Speeckaert MM (male) 2008 2.46±2.24 ug/L 6
Speeckaert MM (female) 2008 4.4±3.3 ug/L 6
Olveira G(male) 2012 3.9±4.4 ng/mL 3.2±1.5 ng/mL R1=0.72; R2=0.47; R3=-0.14 5
Olveira G(female) 2012 12.9±11 ng/mL 11.2±4.1 ng/mL 5
Ziai S(NGT)(male) 2012 2.14±1.9 pg/mL 1.57±0.73 pg/mL R1=0.82; R2=0.32 7
Ziai S(AGT)(male) 2012 1.81±1.56 pg/mL 1.57±0.73 pg/mL 7
Ziai S(CFRD)(male) 2012 4.1±3.66 pg/mL 1.57±0.73 pg/mL 7
Ziai S(NGT)(female) 2012 9.24±5.2 pg/mL 9.1±6.33 pg/mL 7
Ziai S(AGT)(female) 2012 9.17±4.13 pg/mL 9.1±6.33 pg/mL 7
Ziai S(CFRD)(female) 2012 6.87±4.57 pg/mL 9.1±6.33 pg/mL 7
Monajemzadeh M(male) 2013 27.16±33.8 ug/L 5.15±6.41 ug/L 7
Monajemzadeh M(female) 2013 13.85±16.8 ug/L 8.37±9.08 ug/L 7
Nowak JK 2020 R3=-0.1
Polito R 2019 9.2±11.2 ng/mL 12±6.1 ng/mL 8
Granados A(NGT) 2021 14.62±14.3 ug/L 27.7±21.01 ug/L R1=0.31; R2=0.3 7
Granados A(AGT) 2021 12.05±16.3 ug/L 27.7±21.01 ug/L 7
Granados A(CFRD) 2021 7.9±7.3 ug/L 27.7±21.01 ug/L 7
Galiniak S(male) 2022 12.17±5.65 ng/mL 4.97±1.58 ng/mL R1=0.5025; R2=0.649; R3=-0.494 8
Galiniak S(female) 2022 15.78±7.85 ng/mL 7.43±2.7 ng/mL 8

NOS, Newcastle-Ottawa Scale; R1, correlation coefficient between leptin concentrations and fat mass; R2, correlation coefficient between leptin concentrations and BMI; R3, correlation coefficient between leptin concentrations and FEV1; NGT, normal glucose tolerance; AGT, abnormal glucose tolerance; CFRD, cystic fibrosis-related diabetes; IGT, impaired glucose tolerance.