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. 2023 Mar 27;20(6):558–569. doi: 10.1038/s41423-023-00998-y

Table 1.

Clinical trials for DSCs (source: https://www.clinicaltrials.gov/)

Disease Infusion method Sample size Cell mass Cell source Study phase NCT number Location
COVID-19 Intravenously infusion 20 3 × 10^7 cells DPSCs Recruiting NCT04336254 China
Periodontitis Local injection 36 1  × 10^6–4  × 10^7 cells DPSCs Recruiting NCT04983225 China
Acute Ischemic Stroke Intravenously infusion 79 1 or 3  × 10^8 cells DPSCs Completed NCT04608838 Japan
Cleft Lip and Palate Local implantation 62 N/A DPSCs Completed NCT03766217 Brazil
Knee Osteoarthritis Intraarticular injection 60 N/A DPSCs Unknown NCT04130100 China
Periodontal Diseases Local implantation 29 N/A DPSCs Completed NCT03386877 Italy
Periodontal Diseases Local injection 40 1 × 10^6 cells DPSCs Unknown NCT02523651 China
Periodontal tissue regeneration Local implantation 30 N/A PDLSCs Completed NCT01357785 China
Periodontitis Local implantation 80 N/A PDLSCs Completed NCT01082822 China
Periodontal Intrabony Defect Local implantation 20 N/A GMSCs Completed NCT03638154 Egypt
Periodontitis Local implantation 30 N/A GMSCs Unknown NCT03137979 China
Liver Cirrhosis Peripheral vein infusion 40 1 × 10^6 cells/kg SHEDs Unknown NCT03957655 China
Cleft Lip and Palate Local implantation 5 N/A SHEDs Completed NCT01932164 Brazil
Type 2 Diabetes Intravenous drip 24 0.1 IU/kg SHEDs Completed NCT03658655 China
Dental Pulp Necrosis Local implantation 80 N/A SHEDs Unknown NCT01814436 China
Type 1 Diabetes Intravenously infusion 24 0.11 IU/kg SHEDs Unknown NCT03912480 China