Table 1.
Clinical characteristics of patients with CIEDs who developed non-SA GPC bacteremia from 2012 to 2019
| Characteristic | Rejected CIED infection (n = 70) | Definite/possible CIED infection (n = 90) | P value |
|---|---|---|---|
| Male | 48 (68.6) | 68 (75.6) | .326∗ |
| Age, y | 75.5 (63.0–85.4) | 72.8 (61.8–82.4) | .196† |
| BMI, kg/m2 | 28.9 (24.4–35.0) | 26.2 (24.0–32.5) | .159† |
| Comorbidities | |||
| Charlson Comorbidity Index | 7 (5–8) | 6 (4–7) | .037† |
| Diabetes mellitus | 21 (30.0) | 37 (41.1) | .147∗ |
| ESRD with dialysis | 7 (10.0) | 6 (6.7) | .444∗ |
| Moderate or severe liver disease | 2 (2.9) | 1 (1.1) | .419∗ |
| Malignancy | 15 (21.4) | 11 (12.2) | .117∗ |
| Prosthetic heart valve | 3 (4.3) | 44 (48.9) | <.001∗ |
| Annuloplasty or other valve repairs | 1 (1.4) | 7 (7.8) | .068∗ |
| Other valvular abnormality | 8 (11.4) | 14 (15.6) | .452∗ |
| Congenital heart diseases | 0 (0.0) | 6 (6.7) | .028∗ |
| Type of current device | .121∗ | ||
| PPM | 42 (60.0) | 56 (62.2) | |
| AICD | 25 (35.7) | 23 (25.6) | |
| CRT | 3 (4.3) | 11 (12.2) | |
| Duration of bacteremia, d | 1 (1–2) | 3 (2–4) | <.001† |
| Type of bacteremia | .002∗ | ||
| Community acquired | 34 (48.6) | 66 (73.3) | |
| Healthcare associated | 24 (34.3) | 11 (12.2) | |
| Nosocomial | 12 (17.1) | 13 (14.4) | |
Values are n (%) or median (interquartile range)
AICD = automatic implantable cardioverter-defibrillator; BMI = body mass index; CIED = cardiovascular implantable electronic device; CRT = cardiac resynchronization therapy; ESRD = end-stage renal disease; GPC = gram-positive cocci; PPM = permanent pacemaker; SA = Staphylococcus aureus.
∗
Pearson chi-square test.
†
Wilcoxon rank sum test.