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. 2023 Mar 27;22(5):387–409. doi: 10.1038/s41573-023-00670-0

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Fig. 1 — This timeline illustrates examples of several key delivery technologies and drug delivery systems (DDSs) developed between the 1950s and the 2020s, many of which have improved or are expected to improve patient adherence. Several technologies currently in development that may be featured in future DDSs are also included. ADHD, attention deficit hyperactivity disorder; GLP1RA, glucagon-like peptide 1 receptor agonist; HIV, human immunodeficiency virus; IUD, intrauterine device; PrEP, pre-exposure prophylaxis.