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. 2023 Mar 3;66(6):3818–3851. doi: 10.1021/acs.jmedchem.2c01360

Figure 10.

Figure 10

Influence of the side chain at P1 in depicted dipeptide nitriles on their inhibitory selectivity for cathepsins B, S, L, and K. The measurement was performed in three independent experiments (each as a duplicate determination) in assay buffer (pH 6.0) containing 1.5% DMSO.