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. 2023 Mar 3;66(6):3818–3851. doi: 10.1021/acs.jmedchem.2c01360

Figure 7.

Figure 7

Inhibition of cathepsin B by dipeptide alkyne 2b. (A) Turnover of Z-RR-AMC by cathepsin B in the presence of increasing concentrations of dipeptide alkyne 2b. (B and C) Replots of pseudo-first-order rate constants, kobs, and initial velocities, v0, respectively, vs inhibitor concentration.