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. 2023 Mar 27;20:85. doi: 10.1186/s12974-023-02763-4

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Macula and optic disc regions of each included study which were measured for vascular, perfusion, and flow density. A Illustration of retinal fundus and location of the macula and optic disc segments. Foveal avascular zone (FAZ) parts are also displayed in the left circle. B Fields analyzed in each study. Blue shows sections of macula and green shows sections of the optic disc. * indicates studies using an Optovue machine, ** Indicates studies using a Zeiss machine. *** indicates studies using a prototype Axsun SS-OCT machine, **** indicates studies using a Nidek machine, ***** indicates studies using a Heidelberg machine, and ****** indicates studies using a Topcon machine. Note: Parts of the figure were drawn using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/)