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. Author manuscript; available in PMC: 2023 Mar 27.
Published in final edited form as: Psychopharmacology (Berl). 2021 Mar 25;238(7):1885–1897. doi: 10.1007/s00213-021-05816-9

Figure 5. Effect of FR manipulations on fentanyl vs. food choice.

Figure 5.

(A) Experimental timeline of Experiment 3C. (B) Fentanyl choice: Percent fentanyl choice across within-session fentanyl unit doses following FR response requirement manipulations in rats after completion of Experiment 3B. Left: Within-session fentanyl-vs.-food choice dose-response function. Right: Total choices completed per component (maximum of 10 choices per component) across the within-session dose-response function. * Difference from baseline schedule (i.e., Food FR5: Drug FR5) at a given unit fentanyl dose, p<0.05. # Significant main effect of FR manipulation, p<0.05. Data are mean ±SEM.