Table 1.
Age group | Subject | Sex | Diagnosis | BARS total | SARA total | MDS-UPDRS total | PROM-Ataxia total | EQ-5D-VAS (100–0) |
---|---|---|---|---|---|---|---|---|
30–40 | 1 | F | SCA3 | 0.75 | 0.8 | 1 | 73 | 67.5 |
2 | M | SCA3 | 5.75 | 5.5 | 6.5 | 64.5 | 82.5 | |
3 | F | Control | 0 | 0 | 0 | 23.5 | 100 | |
4 | F | SCA3 | 19.75 | 19.9 | 41.5 | 107 | 83 | |
5 | F | SCA3 | 14 | 15.8 | 38.5 | 123 | 77.5 | |
6 | F | SCA3 | 0.25 | 1.3 | 3.5 | 54 | 73 | |
41–50 | 7 | F | SCA3 | 15 | 18.1 | 41 | 117 | 35 |
8 | M | SCA3 | 5 | 6.5 | 19.5 | 69.5 | 60 | |
9 | M | SCA3 | 17 | 17.5 | 28 | 152.5 | 78.5 | |
10 | M | SCA3 | 21 | 25.8 | 50.5 | 167.5 | 67.5 | |
11 | F | Control | 0 | 0 | 2 | 16 | 82.5 | |
12 | M | SCA3 | 5.75 | 5.8 | 11.5 | 19.5 | 77.5 | |
13 | F | Control | 0 | 0 | 0 | 9 | 97 | |
14 | F | SCA1 | 11 | 13.4 | 36.2 | 131 | 50 | |
15 | F | SCA3 | 4.25 | 4.8 | 9 | 53 | 92.5 | |
16 | F | SCA2 | 9.5 | 11.8 | 26 | 128 | 77.5 | |
51–60 | 17 | F | Control | 0 | 0 | 0 | 12.5 | 94 |
18 | M | SCA2 | 17 | 16.8 | 29.5 | 138 | 89.5 | |
19 | F | SCA3 | 13.75 | 16.3 | 22 | 118.5 | 44.5 | |
20 | M | MSA-C | 16.5 | 19.3 | 48 | 177.5 | 62 | |
21 | M | Control | 0 | 0 | 0 | 26 | 87.5 | |
22 | F | SCA3 | 8.75 | 11.5 | 23.5 | 72.5 | 81 | |
23 | M | SCA1 | 13.75 | 14.1 | 37 | 77.5 | 50 | |
24 | F | MSA-C | 18.5 | 18.7 | 31.7 | 181.5 | 57 | |
25 | M | SCA3 | 10.5 | 9.8 | 15.5 | 31 | 87 | |
26 | M | SCA3 | 10.75 | 9.8 | 18 | 21 | 94.5 | |
27 | F | SCA6 | 5.5 | 5 | 12 | 49 | 90.5 | |
28 | F | SCA3 | 9.25 | 13.5 | 21 | 56 | 93.5 | |
29 | M | SCA3 | 1.5 | 1.5 | 7 | 44.5 | 88.5 | |
61–72 | 30 | M | SCA3 | 11.75 | 11.5 | 16.5 | 152.5 | 27.5 |
31 | M | MSA-C | 17.75 | 20.2 | 56.5 | 149.5 | 38 | |
32 | F | Control | 0 | 0 | 0 | 47.5 | 81 | |
33 | F | SCA1 | 9.75 | 11 | 17.5 | 91.5 | 50 | |
34 | F | Control | 0 | 0 | 1 | 29 | 86.5 | |
35 | F | MSA-C | 7.25 | 8.3 | 14.5 | 112.5 | 40 | |
36 | F | MSA-C | 13 | 16 | 25.5 | 140 | 71.5 | |
37 | M | Control | 1.5 | 3.5 | 7 | 16.5 | 90 | |
38 | M | MSA-C | 14.5 | 16 | 28.5 | 90 | 85 | |
39 | M | SCA3 | 16.75 | 16.3 | 40 | 145 | 88.5 | |
40 | M | SCA6 | 2.5 | 1 | 6 | 67.5 | 96.5 | |
41 | M | SCA6 | 5.5 | 3 | 4 | 56 | 90 | |
42 | F | SCA3 | 14.75 | 17 | 24 | 142 | 79 |
Average SARA/BARS scores from the two virtual assessors are shown. Some total scores contain fractions of a point due to the linear scaling procedure applied for missing subscores (see ‘Materials and methods’ section). BARS, Brief Ataxia Rating Scale; EQ-5D-VAS, EuroQOL-5D-Visual Analogue Scale; PROM-Ataxia, Patient-Reported Outcome Measure of Ataxia; SARA, Scale for the assessment and rating of ataxia; UPDRS, Unified Parkinson’s Disease Rating Scale.