| 4.1 Parallel‐group trials and first‐period cross‐over trials: comparison of raters |
46 |
7965 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.73 [‐0.85, ‐0.60] |
| 4.1.1 Teacher‐rated |
21 |
1759 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.75 [‐0.90, ‐0.60] |
| 4.1.2 Independent assessor‐rated |
20 |
3601 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.88 [‐1.18, ‐0.58] |
| 4.1.3 Parent‐rated |
26 |
2605 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.64 [‐0.77, ‐0.51] |
| 4.2 Parallel‐group trials and first‐period cross‐over trials: age |
13 |
2374 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.93 [‐1.35, ‐0.50] |
| 4.2.1 2 to 6 years |
2 |
153 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.50 [‐0.82, ‐0.18] |
| 4.2.2 7 to 11 years |
5 |
623 |
Std. Mean Difference (IV, Random, 95% CI) |
‐1.77 [‐3.24, ‐0.29] |
| 4.2.3 12 to 18 years |
6 |
1598 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.48 [‐0.77, ‐0.19] |
| 4.3 Parallel‐group trials and first‐period cross‐over trials: comorbidity versus no comorbidity |
29 |
3433 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.69 [‐0.84, ‐0.54] |
| 4.3.1 ADHD with comorbidity |
20 |
2128 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.67 [‐0.88, ‐0.47] |
| 4.3.2 ADHD without comorbidity |
9 |
1305 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.73 [‐0.91, ‐0.54] |
| 4.4 Parallel‐group trials and first‐period cross‐over trials: subtypes ADHD: ADHD Rating Scale (parent‐, teacher‐ or independent assessor‐rated) |
2 |
|
Std. Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 4.4.1 Combined ADHD |
2 |
559 |
Std. Mean Difference (IV, Random, 95% CI) |
0.65 [‐1.30, 2.60] |
| 4.4.2 Inattentive ADHD |
1 |
204 |
Std. Mean Difference (IV, Random, 95% CI) |
‐1.31 [‐1.61, ‐1.01] |
| 4.5 Cross‐over trials: first‐period data versus endpoint data (parent‐, independent assessor‐ and teacher‐rated) |
4 |
|
Std. Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 4.5.1 First‐period data |
4 |
191 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.64 [‐0.93, ‐0.34] |
| 4.5.2 Endpoint data |
4 |
372 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.91 [‐1.18, ‐0.65] |
