Chan 2010.

Methods	Setting: Clinics, Hong Kong Recruitment: Community volunteers & clinic patients, motivated to quit
Participants	719 male smokers with erectile dysfunction, av. age 49, av. cpd 20 Provider: Specialist counsellor
Interventions	1, Counselling at 0, 1, 4wks, ˜15 min, NRT (patch or gum) for 2 wks. +/‐ 5 min adherence intervention (pooled for cessation outcomes) 2. Brief advice, 10 min, S‐H materials
Outcomes	Abstinence at 6m (PP) Validation: cotinine 115 ng/mL,  CO > 8ppm
Notes	Study stopped early before reaching target, when abstinence differences significant. Not included in subgroup by setting as recruitment included both community volunteers and clinic patients
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Randomly assigned in 2 stages, no details reported
Allocation concealment (selection bias)	Unclear risk	No details given, 'single blind'
Incomplete outcome data (attrition bias) All outcomes	Low risk	24‐30% lost to follow‐up