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. 2016 Mar 24;2016(3):CD008286. doi: 10.1002/14651858.CD008286.pub3

Cooney 2007.

Methods Setting: 2 Veterans Administration outpatient substance abuse programmes, USA
 Recruitment: Patients in treatment programme, interested in smoking cessation & alcohol treatment
Participants 118 smokers, ≥ 10 cpd, (excludes 15 early dropouts); 89% M, av. age 47, av. cpd 25
Provider: cessation specialist
Interventions 1. Brief advice; 5As model, 15 min session & 5 min follow‐up, no offer of NRT
 2. Intensive intervention; 3x 60 min individual sessions, free NRT (21 mg patch for up to 8 wks including tapering)
 Both delivered concurrently with 3 week intensive substance abuse programme (15 meetings)
Outcomes Abstinence at 6 months (PP)
 Validation: CO < 10 ppm
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Randomized, method not stated
Allocation concealment (selection bias) Unclear risk No details given
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 9 I & 6 C pre‐therapy dropouts excluded. Lost to follow‐up: 9/55 (16%) I, 14/63 (22%) C. Losses included as smokers; exclusion would reduce point estimate, but CIs wide.