Figure 2.

Body weight (A), growth rate (B), lean mass (C), fat mass (D), water mass (E) of male C57BL/6 mice in early life ambulatory controls (CON) and those exposed to early life PIA (PIA) as hindlimb unloading (HU) in the early postnatal period (days P28–42) and during 4-mo recovery (days P42–140) and effects in early adulthood when exposed to HU and HU + 7 days of reloading (RL7). Body weight changes during PIA (F) growth rate during 7 days of reloading following HU (G) in early adulthood mice in ambulatory controls (CON) and those exposed to early life PIA (PIA). Early life controls (CON) and PIA (PIA) mice body weight (H) and tissue composition (I–K) at sack in early adulthood (5 mo) in ambulatory controls (AMB), exposed to HU or HU + 7 days of reloading. PIA, physical inactivity.