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Multivariate analysis carried out on the 37 top most significantly changed proteins between HMW-HA vs. vehicle (C) using the data from Table 4. Two-dimensional (2-D) HCA heat map (A) and three-dimensional (3-D) PCA plot (B) of control (C) vs. HMW-HA-treated (HA) rat L2 cells. Each column of the heat map and each point of the PCA represents a different experiment. HA, hyaluronan (hyaluronic acid); HMW, high molecular weight; PCA, principal component analysis.
