Figure 8.

Cell cycle analysis of confluent rat L2 cells incubated with S1 protein (100 ng) for 24 h or pretreated with HMW-HA (200 ng/mL) for 1 h prior to incubation with S1 protein. Cell cycle analysis was conducted as described in the materials and methods. Values are means with standard error of the means and individual values. One-way analysis of variance followed by the Tukey’s t test for multiple comparisons. Data from two different batches of cells. HA, hyaluronan (hyaluronic acid); HMW, high molecular weight.