Measurements of total plasma nitrate/nitrite to endothelin-1 ratio pre- and postprolonged sitting in a control group (CON, no movement), passive leg movement group (PASS, passive leg movements every 30 min for 2 min at 1 Hz), and active leg movement group (ACT, active leg movements every 30 min for 2 min at 1 Hz at a 13-W workload). Total plasma nitrate/nitrite to endothelin-1 ratio was lower in post-CON and post-PASS when compared with post-ACT. n = 14, †P < 0.05 vs. PASS. [Adapted and reused with permission from Park et al. (8).]