Table 2. Serum hormones of participants according to fertility status (n=827).
Variable | Idiopathic MFI | Unexplained MFI | Fertile | p-valuea | |
---|---|---|---|---|---|
No. of individuals (%) | 570 (68.9) | 154 (18.6) | 103 (12.5) | ||
TT (ng/mL) | 0.2 | ||||
Median (IQR) | 5.2 (4.2–6.2) | 5.4 (4.0–6.3) | 4.9 (4.1–5.9) | ||
Range | 3.1–14.3 | 3.1–9.9 | 2.4–9.2 | ||
FSH (mUI/mL) | 0.1 | ||||
Median (IQR) | 4.5 (3.0–7.7) | 4.6 (2.3–6.2) | 4.1 (3.0–5.6) | ||
Range | 1.0–19.6 | 1.0–13.1 | 1.4–12.6 | ||
LH (mUI/mL) | 0.02 | ||||
Median (IQR) | 3.9 (2.8–5.4) | 3.5 (2.8–5.1) | 4.3 (3.6–5.5)b,c | ||
Range | 0.9–16.0 | 1.6–8.7 | 1.5–10.4 | ||
Prolactin (ng/mL) | 0.5 | ||||
Median (IQR) | 8.8 (6.5–12.5) | 8.5 (6.6–11.1) | |||
Range | 1.9–59.4 | 2.6–75.3 | |||
SHBG (nmol/L) | 0.6 | ||||
Median (IQR) | 34.1 (27–42) | 36.0 (27–45) | |||
Range | 11.1–154.0 | 15.0–75.0 | |||
TSH (mUI/L) | 0.1 | ||||
Median (IQR) | 1.7 (1.2–2.3) | 1.6 (1.1–2.2) | |||
Range | 0.3–9.0 | 0.9–5.4 | |||
Inhibin B (pg/mL) | 0.2 | ||||
Median (IQR) | 141 (87–199) | 150 (123–190) | |||
Range | 0.7–538.0 | 18.0–305.0 | |||
Vitamin D (ng/mL) | 0.01 | ||||
No. of individuals (%) | 106 (18.6) | 87 (56.5) | |||
Median (IQR) | 22.3 (17.8–28.05) | 31.6 (21.4–45.2) | |||
Range | 8.8–128.0 | 18.7–52.2 | |||
Vitamin D <20 ng/mL, n (%) | 215 (37.7) | 13 (8.4) | <0.01 |
MFI: male factor infertility, TT: total testosterone, IQR: interquartile range, FSH: follicle-stimulating hormone, LH: luteinizing hormone, SHBG: sex hormone binding globulin, TSH: thyroid-stimulating hormone.
ap value according to the Kruskal–Wallis test and Fisher exact test, as indicated. bp<0.01 vs. idiopathic group. cp<0.01 vs. unexplained group.