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. 2023 Mar 3;15(5):1543–1563. doi: 10.18632/aging.204561

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Copyright: © 2023 Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Survival analysis of potential prognostic biomarkers and identification of the core genes. Results of (A) OS and (B) PFS survival analysis for the potential prognostic biomarkers. (C) Relationship between LIFR expression and OS. (D) Relationship between TFAP2A expression and OS. (E) Relationship between TFAP2A expression and PFS. Correlation studies of potential prognostic genes with MSI, in which (F) CAV1 was significantly associated with MSI, while (G) LIFR was non-significantly associated with MSI as well as (H) TFAP2A was significantly associated with MSI. (I) Lollipop charts of the mutation landscape of TFAP2A, showing a somatic mutation rate is 0.98%. (J) Protein expression of TFAP2A in normal and LUAD tissues in pathological sections, indicating that TFAP2A was highly expressed in LUAD samples.